BMX (phospho Y566)polyclonal antibody
产品名称： BMX (phospho Y566)polyclonal antibody
英文名称： BMX (phospho Y566)polyclonal antibody
产品编号： PAB15894
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of BMX.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding Y566 of human BMX.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:2000-1:5000)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases.
Nore BF, Mattsson PT, Antonsson P, Backesjo CM, Westlund A, Lennartsson J, Hansson H, Low P, Ronnstrand L, Smith CI.Biochim Biophys Acta. 2003 Feb 21;1645(2):123-32.
- 2.
- Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking.
Yang J, Kim O, Wu J, Qiu Y.J Biol Chem. 2002 Aug 16;277(33):30219-26. Epub 2002 Mar 4.
- 3.
- Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells.
Qiu Y, Robinson D, Pretlow TG, Kung HJ.Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3644-9.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 660
- Gene Name:
- BMX
- Gene Alias:
- ETK,PSCTK2,PSCTK3
- Gene Description:
- BMX non-receptor tyrosine kinase
- Omim ID:
- 300101
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified
- Other Designations:
- OTTHUMP00000022964,OTTHUMP00000022965,OTTHUMP00000022966
- Related Disease