CrkII Mouse Monoclonal Antibody
产品名称: CrkII Mouse Monoclonal Antibody
英文名称: CrkII Mouse Monoclonal Antibody
产品编号: K000084M
产品价格: null
产品产地: 北京市通州区马驹桥
品牌商标: solarbio
更新时间: 2025-01-02T09:53:49
使用范围: WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
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- 邮箱 : 3193328036@qq.com
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Anti-CrkII Monoclonal Antibody
品牌:solarbio | 货号:K000084M
英文名称 Anti-CrkII Monoclonal Antibody 宿主 Mouse 别名 CRKII;p38 应用 WB 稀释比例 WB 1:1000. 交叉反应 Human 蛋白分子量 34kDa Gene ID 1398 保存 Store at -20°C. Avoid freeze / thaw cycles. 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 纯化方法 Affinity purification 亚型 IgG2b 免疫原 Purified recombinant human CrkII protein fragments expressed in E.coli. 性状 液体 Public Immunogen Range Purified recombinant human CrkII protein fragments expressed in E.coli. Subcellular Locations Cell membrane Cytoplasm Swiss Prot P46108 克隆号 3H7-E5-H8 克隆类型 Monoclonal Antibody 背景资料 This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.