CrkII Mouse Monoclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
CrkII Mouse Monoclonal Antibody

CrkII Mouse Monoclonal Antibody

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产品名称: CrkII Mouse Monoclonal Antibody

英文名称: CrkII Mouse Monoclonal Antibody

产品编号: K000084M

产品价格: null

产品产地: 北京市通州区马驹桥

品牌商标: solarbio

更新时间: 2025-01-02T09:53:49

使用范围: WB

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Anti-CrkII Monoclonal Antibody

品牌:solarbio | 货号:K000084M




英文名称Anti-CrkII Monoclonal Antibody
宿主Mouse
别名CRKII;p38
应用WB
稀释比例WB 1:1000.
交叉反应Human
蛋白分子量34kDa
Gene ID1398
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG2b
免疫原Purified recombinant human CrkII protein fragments expressed in E.coli.
性状液体
Public Immunogen RangePurified recombinant human CrkII protein fragments expressed in E.coli.
Subcellular LocationsCell membrane Cytoplasm
Swiss ProtP46108
克隆号3H7-E5-H8
克隆类型Monoclonal Antibody
背景资料This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.