IRF5 polyclonal antibody
产品名称: IRF5 polyclonal antibody
英文名称: IRF5 polyclonal antibody
产品编号: PAB6227
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of IRF5.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human IRF5.
- Sequence:
- C-QGPWPMHPAGMQ
- Host:
- Goat
- Theoretical MW (kDa):
- 57.8
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize all four reported isoforms (NP_002191.1, NP_1160.32.1, NP_001092097.1, NP_001092099.1). Reported variants represent identical protein: NP_001092101.1, NP_001092098.1, NP_001092097.1 Reported variants represent identical protein: NP_1160.32.1, NP_001092100.1
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit.
Ning S, Huye LE, Pagano JS.J Virol. 2005 Sep;79(18):11671-6.
- Applications
- Western Blot (Cell lysate)
- IRF5 polyclonal antibody (Cat # PAB6227) staining (2 ug/mL) of A-549 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
- Entrez GeneID:
- 3663
- Protein Accession#:
- NP_002191.1;NP_1160.32.1;NP_001092097.1;NP_001092099.1
- Gene Name:
- IRF5
- Gene Alias:
- SLEB10
- Gene Description:
- interferon regulatory factor 5
- Omim ID:
- 607218
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. [provided by RefSeq
- Other Designations:
- -
- Gene Pathway
- Related Disease
- Antiphospholipid Syndrome
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Autoimmune Diseases
- Behcet Syndrome
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Carotid Stenosis
- Cerebral Hemorrhage
- Crohn's disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Endometriosis