PDGFRB polyclonal antibody
产品名称: PDGFRB polyclonal antibody
英文名称: PDGFRB polyclonal antibody
产品编号: PAB18498
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PDGFRB.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding Y751 of human PDGFRB.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to PDGFRB.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV.
Sanders MA, Basson MD.J Biol Chem. 2005 Jun 24;280(25):23516-22. Epub 2005 Apr 6.
- 2.
- Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.
Cherubini A, Hofmann G, Pillozzi S, Guasti L, Crociani O, Cilia E, Di Stefano P, Degani S, Balzi M, Olivotto M, Wanke E, Becchetti A, Defilippi P, Wymore R, Arcangeli A.Mol Biol Cell. 2005 Jun;16(6):2972-83. Epub 2005 Mar 30.
- 3.
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, KGenome Res. 2004 Oct;14(10B):2121-7.
- 4.
- Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase.
Toriumi Y, Hiraoka M, Watanabe M, Yoshida M.FEBS Lett. 2003 Oct 23;553(3):419-22.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from LoVo cells, using PDGFRB polyclonal antibody (Cat # PAB18498).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 5159
- Protein Accession#:
- P09619
- Gene Name:
- PDGFRB
- Gene Alias:
- CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1
- Gene Description:
- platelet-derived growth factor receptor, beta polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
- Other Designations:
- beta platelet-derived growth factor receptor,platelet-derived growth factor receptor beta,soluble PDGFRb variant 1
- Interactome
- Related Disease
- Acute Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hyperparathyroidism, Secondary
- Kidney Failure, Chronic
- Leukemia, Myeloid
- Metabolic Syndrome X
- Neoplasms
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