Anti-BAX Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002397P-50ul	solarbio	50ul	960.00元
K002397P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-BAX Polyclonal Antibody
别名	BCL2L4
应用	WB IHC IF IP
稀释比例	WB 1:500-2000. IHC 1:100-200. IF 1:50-200. IP 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	21kDa
Gene ID	581
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human BAX
性状	液体
Public Immunogen Range	A synthetic peptide of human BAX
Subcellular Locations	Cytoplasm Cytoplasm Mitochondrion membrane Single-pass membrane protein
Swiss Prot	Q07812
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.